4zzy: Difference between revisions
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==Structure of human PARP2 catalytic domain bound to an isoindolinone inhibitor== | ==Structure of human PARP2 catalytic domain bound to an isoindolinone inhibitor== | ||
<StructureSection load='4zzy' size='340' side='right' caption='[[4zzy]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='4zzy' size='340' side='right' caption='[[4zzy]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4zzy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZZY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZZY FirstGlance]. <br> | <table><tr><td colspan='2'>[[4zzy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZZY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZZY FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D7N:2-[1-(4,4-DIFLUOROCYCLOHEXYL)-PIPERIDIN-4-YL]-6-FLUORO-3-OXO-2,3-DIHYDRO-1H-ISOINDOLE-4-CARBOXAMIDE'>D7N</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D7N:2-[1-(4,4-DIFLUOROCYCLOHEXYL)-PIPERIDIN-4-YL]-6-FLUORO-3-OXO-2,3-DIHYDRO-1H-ISOINDOLE-4-CARBOXAMIDE'>D7N</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zzx|4zzx]], [[4zzz|4zzz]], [[5a00|5a00]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zzx|4zzx]], [[4zzz|4zzz]], [[5a00|5a00]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zzy OCA], [http://pdbe.org/4zzy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zzy RCSB], [http://www.ebi.ac.uk/pdbsum/4zzy PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zzy OCA], [http://pdbe.org/4zzy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zzy RCSB], [http://www.ebi.ac.uk/pdbsum/4zzy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zzy ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Borghi, D]] | [[Category: Borghi, D]] | ||
[[Category: Busel, A A]] | [[Category: Busel, A A]] | ||
