4y63: Difference between revisions
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==AAGlyB in complex with amino-acid analogues== | |||
<StructureSection load='4y63' size='340' side='right' caption='[[4y63]], [[Resolution|resolution]] 1.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4y63]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y63 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y63 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=48O:5-DEOXY-5-{[(2S)-2-(TRIAZA-1,2-DIEN-2-IUM-1-YL)PROPANOYL]AMINO}URIDINE'>48O</scene>, <scene name='pdbligand=BHE:OCTYL+2-O-(6-DEOXY-ALPHA-L-GALACTOPYRANOSYL)-BETA-D-GALACTOPYRANOSIDE'>BHE</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | |||
[[Category: | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ABO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
[[Category: Cuesta-Seijo, J | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y63 OCA], [http://pdbe.org/4y63 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y63 RCSB], [http://www.ebi.ac.uk/pdbsum/4y63 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y63 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN]] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Human]] | |||
[[Category: Cuesta-Seijo, J A]] | |||
[[Category: Lafont, D]] | |||
[[Category: Palcic, M M]] | |||
[[Category: Striebeck, A]] | [[Category: Striebeck, A]] | ||
[[Category: Vidal, S]] | [[Category: Vidal, S]] | ||
[[Category: | [[Category: Wang, S]] | ||
[[Category: Aaglyb]] | |||
[[Category: Inhibitor]] | |||
[[Category: Transferase]] | |||
Revision as of 17:02, 16 November 2017
AAGlyB in complex with amino-acid analogues
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