4wpt: Difference between revisions
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==Crystal Structure of Mtb PEPCK in complex with PEP== | |||
<StructureSection load='4wpt' size='340' side='right' caption='[[4wpt]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4wpt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycta Mycta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WPT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WPT FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wou|4wou]], [[4wl8|4wl8]], [[4wiu|4wiu]], [[4wpu|4wpu]], [[4wpv|4wpv]], [[4pie|4pie]]</td></tr> | ||
[[Category: Krieger, I | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pckG, MRA_0219 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=419947 MYCTA])</td></tr> | ||
[[Category: Sacchettini, J | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(GTP) Phosphoenolpyruvate carboxykinase (GTP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.32 4.1.1.32] </span></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wpt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wpt OCA], [http://pdbe.org/4wpt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wpt RCSB], [http://www.ebi.ac.uk/pdbsum/4wpt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wpt ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/PCKG_MYCTA PCKG_MYCTA]] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Mycta]] | |||
[[Category: Kim, H L]] | |||
[[Category: Krieger, I V]] | |||
[[Category: Sacchettini, J C]] | |||
[[Category: Anaplerotic reaction]] | |||
[[Category: Gtp-dependent pepck]] | |||
[[Category: Lyase]] | |||
[[Category: Omega-loop]] | |||
[[Category: P-loop]] | |||
[[Category: R-loop]] | |||
[[Category: Transferase]] | |||
Revision as of 09:28, 22 November 2017
Crystal Structure of Mtb PEPCK in complex with PEP
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