5wqc: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5wqc is ~~ON HOLD until Paper Publication~~

==Crystal structure of human orexin 2 receptor bound to the selective antagonist EMPA determined by the synchrotron light source at SPring-8.==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5wqc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WQC FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=7MA:N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide'>7MA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wqc OCA], [http://pdbe.org/5wqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wqc RCSB], [http://www.ebi.ac.uk/pdbsum/5wqc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wqc ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/OX2R_HUMAN OX2R_HUMAN]] Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides.

__TOC__

</StructureSection>

[[Category: Hirata, K]]

[[Category: Horita, S]]

[[Category: Iwata, S]]

[[Category: Kobayashi, T]]

[[Category: Rosenbaum, D M]]

[[Category: Sasanuma, M]]

[[Category: Shimamura, T]]

[[Category: Suno, R]]

[[Category: Tsujimoto, H]]

[[Category: Yamamoto, M]]

[[Category: Yamashita, K]]

[[Category: Empa]]

[[Category: G protein-coupled receptor]]

[[Category: N-linked glycosylation]]

[[Category: Orexin 2 receptor]]

[[Category: Orexin neurotransmitter]]

[[Category: Orexin-a]]

[[Category: Orexin-b]]

[[Category: Signaling protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5wqc is ON HOLD  until Paper Publication
+==Crystal structure of human orexin 2 receptor bound to the selective antagonist EMPA determined by the synchrotron light source at SPring-8.==
+<StructureSection load='5wqc' size='340' side='right' caption='[[5wqc]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5wqc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WQC FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=7MA:N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide'>7MA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wqc OCA], [http://pdbe.org/5wqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wqc RCSB], [http://www.ebi.ac.uk/pdbsum/5wqc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wqc ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/OX2R_HUMAN OX2R_HUMAN]] Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides.
+__TOC__
+</StructureSection>
+[[Category: Hirata, K]]
+[[Category: Horita, S]]
+[[Category: Iwata, S]]
+[[Category: Kobayashi, T]]
+[[Category: Rosenbaum, D M]]
+[[Category: Sasanuma, M]]
+[[Category: Shimamura, T]]
+[[Category: Suno, R]]
+[[Category: Tsujimoto, H]]
+[[Category: Yamamoto, M]]
+[[Category: Yamashita, K]]
+[[Category: Empa]]
+[[Category: G protein-coupled receptor]]
+[[Category: N-linked glycosylation]]
+[[Category: Orexin 2 receptor]]
+[[Category: Orexin neurotransmitter]]
+[[Category: Orexin-a]]
+[[Category: Orexin-b]]
+[[Category: Signaling protein]]