2brb: Difference between revisions

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|PDB= 2brb |SIZE=350|CAPTION= <scene name='initialview01'>2brb</scene>, resolution 2.10&Aring;
|PDB= 2brb |SIZE=350|CAPTION= <scene name='initialview01'>2brb</scene>, resolution 2.10&Aring;
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Chain+A'>AC1</scene>
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=PFQ:2-[(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)AMINO]ETHANOL'>PFQ</scene>
|LIGAND= <scene name='pdbligand=PFQ:2-[(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)AMINO]ETHANOL'>PFQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferred_entry:_2.7.11.1 Transferred entry: 2.7.11.1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.37 2.7.1.37]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span>
|GENE=  
|GENE=  
|DOMAIN=
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2brb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2brb OCA], [http://www.ebi.ac.uk/pdbsum/2brb PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2brb RCSB]</span>
}}
}}


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Structure-based design of novel Chk1 inhibitors: insights into hydrogen bonding and protein-ligand affinity., Foloppe N, Fisher LM, Howes R, Kierstan P, Potter A, Robertson AG, Surgenor AE, J Med Chem. 2005 Jun 30;48(13):4332-45. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15974586 15974586]
Structure-based design of novel Chk1 inhibitors: insights into hydrogen bonding and protein-ligand affinity., Foloppe N, Fisher LM, Howes R, Kierstan P, Potter A, Robertson AG, Surgenor AE, J Med Chem. 2005 Jun 30;48(13):4332-45. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15974586 15974586]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Transferred entry: 2 7.11 1]]
[[Category: Fisher, L M.]]
[[Category: Fisher, L M.]]
[[Category: Foloppe, N.]]
[[Category: Foloppe, N.]]
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[[Category: Robertson, A G.S.]]
[[Category: Robertson, A G.S.]]
[[Category: Surgenor, A E.]]
[[Category: Surgenor, A E.]]
[[Category: PFQ]]
[[Category: SO4]]
[[Category: drug design]]
[[Category: drug design]]
[[Category: furanopyrimidine]]
[[Category: furanopyrimidine]]
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[[Category: transferase]]
[[Category: transferase]]


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