IspG: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
The substrate <scene name='77/774679/Cv/2'>MEcPP is located in the cavity between the TIM-barrel and the lid domain</scene> of IpsG. <scene name='77/774679/Cv/3'>It binds covalently to the 4Fe4S cluster</scene> and its <scene name='77/774679/Cv/8'>PP moiety binds to 4 Arg and 1 Lys sidechains</scene | The substrate <scene name='77/774679/Cv/2'>MEcPP is located in the cavity between the TIM-barrel and the lid domain</scene> of IpsG. <scene name='77/774679/Cv/3'>It binds covalently to the 4Fe4S cluster</scene> and its <scene name='77/774679/Cv/8'>PP moiety binds to 4 Arg and 1 Lys sidechains</scene>. | ||
*<scene name='77/774679/Cv/6'>4Fe4S cluster binding site</scene>. | *<scene name='77/774679/Cv/6'>4Fe4S cluster binding site</scene>. | ||
*<scene name='77/774679/Cv/7'>Whole active site</scene>. | *<scene name='77/774679/Cv/7'>Whole active site</scene>. | ||
*<scene name='77/774679/Cv/9'>1st Cl coordination site</scene>. | |||
*<scene name='77/774679/Cv/10'>Cl/K cluster coordination site</scene>. | |||
</StructureSection> | </StructureSection> | ||
== 3D Structures of IspG == | == 3D Structures of IspG == | ||
Revision as of 13:15, 30 November 2017
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3D Structures of IspG
Updated on 30-November-2017
3noy – IspG – Aquifex aeolicus
4mwa – IspG – Bacillus anthracis
2y0f – TtIspG – Thermus thermophilus
4s38, 4g9p – TtIspG + MEcPP
4s39, 4s23 – TtIspG + HMBPP
4s3a, 4s3b, 4s3c – TtIspG + intermediate
4s3c – TtIspG + PPi
4s3e, 4s3f – TtIspG + inhibitor