User:Harish Srinivas: Difference between revisions

Signal transduction is a fundamental process at the center of cellular activity and organismal function. The ability of cells to respond to signals in their environment allows adaptive responses central to survival(4). Sphingosine 1 -phosphate (S1P) is a membrane-derived lysophospholipid that acts primarily as an extracellular signaling molecule(1).The pleiotropic sphingolipid mediator, sphingosine 1-phosphate (S1P), exerts many of its functions by binding to a family of five specific S1P receptors (S1PRs)(3).  The S1P receptors are cell-surface class A G-protein coupled receptors (GPCRs), which bind and are activated by the endogenous ligand S1P(3). The S1P1 receptor plays a crucial role in the immune, lymaphatic, vascular and nervous system.