5wt3: Difference between revisions
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==Pyrococcus abyssi methyltransferase PaTrm5a bound by MTA and cognate tRNA== | |||
<StructureSection load='5wt3' size='340' side='right' caption='[[5wt3]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5wt3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WT3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WT3 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MTA:5-DEOXY-5-METHYLTHIOADENOSINE'>MTA</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5wt1|5wt1]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wt3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wt3 OCA], [http://pdbe.org/5wt3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wt3 RCSB], [http://www.ebi.ac.uk/pdbsum/5wt3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wt3 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/TRM5A_PYRAB TRM5A_PYRAB]] Specifically methylates the N1 position of guanosine-37 in tRNA(Phe). In vitro, can also methylate the C7 position of 4-demethylwyosine (imG-14).<ref>PMID:20382657</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Jia, Q]] | |||
[[Category: Wang, C]] | |||
[[Category: Xie, W]] | |||
[[Category: Methyltransferase]] | |||
[[Category: Transferase-rna complex]] | |||
[[Category: Trm5a]] | |||
[[Category: Wyosine hypermodification]] | |||