5mkt: Difference between revisions
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==Crystal structure of mouse prorenin== | |||
<StructureSection load='5mkt' size='340' side='right' caption='[[5mkt]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5mkt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MKT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MKT FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Renin Renin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.15 3.4.23.15] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mkt OCA], [http://pdbe.org/5mkt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mkt RCSB], [http://www.ebi.ac.uk/pdbsum/5mkt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mkt ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/RENI1_MOUSE RENI1_MOUSE]] Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Renin]] | |||
[[Category: Read, R]] | [[Category: Read, R]] | ||
[[Category: Yan, Y]] | [[Category: Yan, Y]] | ||
[[Category: Hydrolase]] | |||
[[Category: Prorenin]] | |||
