Merlin: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs) New page: <StructureSection load='3wa0' size='340' side='right' caption='Mouse merlin FERM domain (grey) complex with HIV-1 Vpr-binding protein C-terminal (gold) (PDB code 3wa0)' scene=''> ==... |
Michal Harel (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='3wa0' size='340' side='right' caption='Mouse merlin FERM domain (grey) complex with HIV-1 Vpr-binding protein C-terminal (gold) (PDB code [[3wa0]])' scene=''> | <StructureSection load='3wa0' size='340' side='right' caption='Mouse merlin FERM domain (grey) complex with HIV-1 Vpr-binding protein C-terminal (gold) (PDB code [[3wa0]])' scene=''> | ||
| Line 5: | Line 4: | ||
== Function == | == Function == | ||
Merlin (Mer) or Moesin-exrin-radixin-like protein is a unique tumor suppressor that inhibits mitogenic signaling at the membrane-cytoskeleton interface<ref>PMID:21167305</ref>. The FERM domain of Mer regulates cell proliferation in response to adhesive signaling<ref>PMID:24726726</ref>. | '''Merlin''' (Mer) or Moesin-exrin-radixin-like protein is a unique tumor suppressor that inhibits mitogenic signaling at the membrane-cytoskeleton interface<ref>PMID:21167305</ref>. The FERM domain of Mer regulates cell proliferation in response to adhesive signaling<ref>PMID:24726726</ref>. | ||
== Disease == | == Disease == | ||
