5yv7: Difference between revisions
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==Racemic X-ray Structure of Calcicludine== | |||
<StructureSection load='5yv7' size='340' side='right' caption='[[5yv7]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5yv7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YV7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YV7 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yv7 OCA], [http://pdbe.org/5yv7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yv7 RCSB], [http://www.ebi.ac.uk/pdbsum/5yv7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yv7 ProSAT]</span></td></tr> | |||
[[ | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/VKTHC_DENAN VKTHC_DENAN]] Potent blocker of high-voltage-activated calcium ion channels in the nanomolar range, particularly the L-type channels in cerebellar granule cells. The sensitivity of L-, N- and P-type channels to CAC is tissue and species-dependent. Blocks the L-type current of cardiac cells, depressing cardiac contractility. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Lei, L]] | [[Category: Lei, L]] | ||
[[Category: Qian, Q]] | [[Category: Qian, Q]] | ||
[[Category: Shuai, G]] | |||
[[Category: Calcicludine]] | |||
[[Category: L-type ca2+ channel]] | |||
[[Category: Racemic crystal]] | |||
[[Category: Toxin]] | |||
