Aconitase: Difference between revisions

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Joel L. Sussman (talk | contribs)
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<!--== Available structures ==
<!--== Available structures ==
In the PDB, nearly all deposited structures are from mammals, [[1l5j]] is from ''E.coli''. Also, only [[2ipy]] shows the IREBP function of cAc---it's also the only from rabbit. There are only two other cAc structures, with and without citrate, also the only from human. All other structures are either cow or pig, and a mutant from pig; all three proteins with several different ligands and inhibitors.
In the PDB, nearly all deposited structures are from mammals, [[1l5j]] is from ''E.coli''. Also, only [[3snp]] shows the IREBP function of cAc---it's also the only from rabbit. There are only two other cAc structures, with and without citrate, also the only from human. All other structures are either cow or pig, and a mutant from pig; all three proteins with several different ligands and inhibitors.


*[[1aco]] - mAc (''Bos taurus'') with ''trans''-aconitate (inhibitor)
*[[1aco]] - mAc (''Bos taurus'') with ''trans''-aconitate (inhibitor)
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*[[2b3x]] - cAc (human) as aconitase with Fe4S4
*[[2b3x]] - cAc (human) as aconitase with Fe4S4
*[[2b3y]] - cAc (human) as aconitase with Fe4S4 and citrate
*[[2b3y]] - cAc (human) as aconitase with Fe4S4 and citrate
*[[2ipy]] - cAc (''Oryctolagus cuniculus'') as IRP1 with ferritin RNA
*[[3snp]] - cAc (''Oryctolagus cuniculus'') as IRP1 with ferritin RNA
*[[5acn]] - mAc (''Sus scrofa'') with Fe3S4 (missing a Fe)
*[[5acn]] - mAc (''Sus scrofa'') with Fe3S4 (missing a Fe)
*[[6acn]] - mAc (''Sus scrofa'') with tricarballylic acid
*[[6acn]] - mAc (''Sus scrofa'') with tricarballylic acid