Aconitase: Difference between revisions
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**[[1amj]], [[1nit]] – cACO - cow<br /> | **[[1amj]], [[1nit]] – cACO - cow<br /> | ||
* ACO+citrate | *ACO+citrate | ||
**[[1c96]] - pACO (mutant)+citrate<br /> | **[[1c96]] - pACO (mutant)+citrate<br /> | ||
**[[1b0m]] - pACO (mutant)+fluorocitrate<br /> | **[[1b0m]] - pACO (mutant)+fluorocitrate<br /> | ||
* ACO+aconitate | *ACO+aconitate | ||
**[[1fgh]] – cACO+4-hydroxy-aconitate <br /> | **[[1fgh]] – cACO+4-hydroxy-aconitate <br /> | ||
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**[[1nis]] - cACO+transaconitate+nitrocitrate<br /> | **[[1nis]] - cACO+transaconitate+nitrocitrate<br /> | ||
* ACO+isocitrate | *ACO+isocitrate | ||
**[[7acn]] - pACO +isocitrate<br /> | **[[7acn]] - pACO +isocitrate<br /> | ||
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}} | }} | ||
<!--== Available structures == | <!--== Available structures == | ||
In the PDB, nearly all deposited structures are from mammals, [[1l5j]] is from ''E.coli''. Also, only [[ | In the PDB, nearly all deposited structures are from mammals, [[1l5j]] is from ''E.coli''. Also, only [[2ipy]] shows the IREBP function of cAc---it's also the only from rabbit. There are only two other cAc structures, with and without citrate, also the only from human. All other structures are either cow or pig, and a mutant from pig; all three proteins with several different ligands and inhibitors. | ||
*[[1aco]] - mAc (''Bos taurus'') with ''trans''-aconitate (inhibitor) | *[[1aco]] - mAc (''Bos taurus'') with ''trans''-aconitate (inhibitor) | ||
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*[[2b3x]] - cAc (human) as aconitase with Fe4S4 | *[[2b3x]] - cAc (human) as aconitase with Fe4S4 | ||
*[[2b3y]] - cAc (human) as aconitase with Fe4S4 and citrate | *[[2b3y]] - cAc (human) as aconitase with Fe4S4 and citrate | ||
*[[ | *[[2ipy]] - cAc (''Oryctolagus cuniculus'') as IRP1 with ferritin RNA | ||
*[[5acn]] - mAc (''Sus scrofa'') with Fe3S4 (missing a Fe) | *[[5acn]] - mAc (''Sus scrofa'') with Fe3S4 (missing a Fe) | ||
*[[6acn]] - mAc (''Sus scrofa'') with tricarballylic acid | *[[6acn]] - mAc (''Sus scrofa'') with tricarballylic acid | ||
