5t4x: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==CRYSTAL STRUCTURE OF PDE6D IN APO-STATE== | |||
<StructureSection load='5t4x' size='340' side='right' caption='[[5t4x]], [[Resolution|resolution]] 1.81Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5t4x]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T4X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T4X FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t4x OCA], [http://pdbe.org/5t4x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t4x RCSB], [http://www.ebi.ac.uk/pdbsum/5t4x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t4x ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[http://www.uniprot.org/uniprot/PDE6D_MOUSE PDE6D_MOUSE]] Promotes the release of prenylated target proteins from cellular membranes (PubMed:22179043). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (PubMed:22179043). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (PubMed:22179043). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.[UniProtKB:O43924][UniProtKB:Q95142]<ref>PMID:10518933</ref> <ref>PMID:15979089</ref> <ref>PMID:22179043</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Qureshi, B M]] | |||
[[Category: Scheerer, P]] | |||
[[Category: Schmidt, A]] | [[Category: Schmidt, A]] | ||
[[Category: | [[Category: Apo-state]] | ||
[[Category: Cellular trafficking]] | |||
[[Category: Farnesyl]] | |||
[[Category: Geranylgeranyl]] | |||
[[Category: Immunoglobulin-like beta sandwitch]] | |||
[[Category: Lipid binding protein]] | |||
[[Category: Membrane dissociation]] | |||
[[Category: Membrane trafficking]] | |||
[[Category: Pde6 delta]] | |||
[[Category: Phosphodiesterase 6]] | |||
[[Category: Prenyl binding protein]] | |||
[[Category: Ras-gtpase]] | |||
[[Category: Rhodopsin]] | |||
[[Category: Rhodopsin kinase]] | |||
[[Category: Transport protein]] | |||
Revision as of 08:25, 10 January 2018
CRYSTAL STRUCTURE OF PDE6D IN APO-STATE
| ||||||||||||
