5mou: Difference between revisions
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==NMR spatial structure of alpha-mammal toxin BeM9== | |||
<StructureSection load='5mou' size='340' side='right' caption='[[5mou]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5mou]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MOU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MOU FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mou FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mou OCA], [http://pdbe.org/5mou PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mou RCSB], [http://www.ebi.ac.uk/pdbsum/5mou PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mou ProSAT]</span></td></tr> | |||
[[ | </table> | ||
[[Category: | == Function == | ||
[[Category: Berkut, A | [[http://www.uniprot.org/uniprot/SCX9_MESEU SCX9_MESEU]] Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. Has paralytic activity in mice. | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Arseniev, A S]] | ||
[[Category: | [[Category: Berkut, A A]] | ||
[[Category: Grishin, E V]] | |||
[[Category: Kuldushev, N A]] | |||
[[Category: Mineev, K S]] | |||
[[Category: Vassilevski, A A]] | |||
[[Category: Protein]] | |||
[[Category: Protein neurotoxin]] | |||