5wyh: Difference between revisions
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==Crystal structure of RidL(1-200) complexed with VPS29== | |||
<StructureSection load='5wyh' size='340' side='right' caption='[[5wyh]], [[Resolution|resolution]] 2.46Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5wyh]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WYH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WYH FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wyh OCA], [http://pdbe.org/5wyh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wyh RCSB], [http://www.ebi.ac.uk/pdbsum/5wyh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wyh ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/VPS29_HUMAN VPS29_HUMAN]] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro).<ref>PMID:15247922</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Jia, D]] | |||
[[Category: Sun, Q]] | |||
[[Category: Yao, J]] | |||
[[Category: Complex vps29 ridl]] | |||
[[Category: Metal binding protein-protein binding complex]] | |||