Sandbox Reserved 1440: Difference between revisions
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== 1NU6 == | == 1NU6 == | ||
<jmol><jmollink><text>View Figure 1a: 1NU6 overview</text><script>exit;figure=1;SCRIPT "http://proteopedia.org/wiki/images/ | <jmol><jmollink><text>View Figure 1a: 1NU6 overview</text><script>exit;figure=1;SCRIPT "http://proteopedia.org/wiki/images/d/d2/1nu6_B.png";spin on</script></jmollink></jmol> | ||
1NU6 protein along with the ligand and catalytic triad displayed. The data was captured with a 2.10 Å resolution. The ligand NDG is not found in the binding site, rather it is bound to the outside of the binding pocket. This indicates that the ligand may be binding to an allosteric site and modulating the activity at the binding site. The ligands present in this model are two sugars (NAD and NDG), a Mercury (II) ion, and water. Of these, the mercury ion is closest to the triad, but is not close enough to represent a binding interaction. NDG however is found near the opening of the binding pocket, and thus may be an allosteric site for the protein. | 1NU6 protein along with the ligand and catalytic triad displayed. The data was captured with a 2.10 Å resolution. The ligand NDG is not found in the binding site, rather it is bound to the outside of the binding pocket. This indicates that the ligand may be binding to an allosteric site and modulating the activity at the binding site. The ligands present in this model are two sugars (NAD and NDG), a Mercury (II) ion, and water. Of these, the mercury ion is closest to the triad, but is not close enough to represent a binding interaction. NDG however is found near the opening of the binding pocket, and thus may be an allosteric site for the protein. | ||
<jmol><jmollink><text>View Figure 1b: 1NU6 Triad</text><script>exit;figure=1;SCRIPT "http://proteopedia.org/wiki/images/ | <jmol><jmollink><text>View Figure 1b: 1NU6 Triad</text><script>exit;figure=1;SCRIPT "http://proteopedia.org/wiki/images/d/d2/1nu6_B.png";zoomto *4</script></jmollink></jmol> | ||
The catalytic triad of the protein is shown in Figure 1b. Important to note that there are no clashes surrounding the site, and thus the model may provide an accurate representation of the binding capabilities of this binding pocket. | The catalytic triad of the protein is shown in Figure 1b. Important to note that there are no clashes surrounding the site, and thus the model may provide an accurate representation of the binding capabilities of this binding pocket. | ||
