5muc: Difference between revisions
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==Crystal structure of the FimH lectin domain in complex with 1,5-Anhydromannitol== | |||
<StructureSection load='5muc' size='340' side='right' caption='[[5muc]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5muc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MUC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MUC FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AH2:1,5-Anhydromannitol'>AH2</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5muc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5muc OCA], [http://pdbe.org/5muc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5muc RCSB], [http://www.ebi.ac.uk/pdbsum/5muc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5muc ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Ernst, B]] | |||
[[Category: Jakob, R P]] | |||
[[Category: Maier, T]] | |||
[[Category: Rabbani, S]] | |||
[[Category: Bladder infection]] | |||
[[Category: Carbohydrate]] | |||
[[Category: Fimh]] | |||
[[Category: Lectin]] | |||
[[Category: Sugar binding protein]] | |||
[[Category: Upec]] | |||
[[Category: Uti]] | |||
Revision as of 06:21, 15 February 2018
Crystal structure of the FimH lectin domain in complex with 1,5-Anhydromannitol
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