5o3g: Difference between revisions
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==Human Brd2(BD2) mutant in complex with AL-Am1== | |||
<StructureSection load='5o3g' size='340' side='right' caption='[[5o3g]], [[Resolution|resolution]] 1.85Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5o3g]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O3G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5O3G FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9J8:(2~{R})-2-[(4~{S})-6-(4-chlorophenyl)-8-methoxy-1-methyl-4~{H}-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-~{N}-ethyl-pent-4-enamide'>9J8</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5o3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o3g OCA], [http://pdbe.org/5o3g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5o3g RCSB], [http://www.ebi.ac.uk/pdbsum/5o3g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5o3g ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN]] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Chan, K H]] | |||
[[Category: Ciulli, A]] | |||
[[Category: Runcie, A C]] | |||
[[Category: Transcription]] | |||
Revision as of 06:25, 15 February 2018
Human Brd2(BD2) mutant in complex with AL-Am1
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