5uqq: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5uqq is ~~ON HOLD until Paper Publication~~

==Crystal structure of 2-methylcitrate synthase from Aspergillus fumigatus==

~~Authors~~: ~~Schlachter~~, C., ~~Chruszcz~~, M.

== Structural highlights ==

<table><tr><td colspan='2'>[[5uqq]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UQQ OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UQQ FirstGlance].

~~Description~~: ~~Crystal structure~~ of 2-methylcitrate synthase ~~from Aspergillus fumigatus~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=SRT:S,R+MESO-TARTARIC+ACID'>SRT</scene></td></tr>

~~[[Category: Unreleased Structures]]~~

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uqq OCA], [http://pdbe.org/5uqq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uqq RCSB], [http://www.ebi.ac.uk/pdbsum/5uqq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uqq ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/PRPC_ASPFM PRPC_ASPFM]] Component of the methylcitrate cycle that catalyzes the synthesis of (2S,3S)-2-methylcitrate from propionyl-CoA and oxaloacetate. Plays an important role in detoxification of propionyl-CoA, an inhibitor of both primary and secondary metabolism. Has also citrate synthase activity using as substrates acetyl-CoA and oxaloacetate. May play a role in virulence.<ref>PMID:16008561</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Chruszcz, M]]

[[Category: Schlachter, C]]

[[Category: 2-methylcitrate synthase]]

[[Category: Citrate synthase]]

[[Category: Mcsa]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5uqq is ON HOLD  until Paper Publication
+==Crystal structure of 2-methylcitrate synthase from Aspergillus fumigatus==
+<StructureSection load='5uqq' size='340' side='right' caption='[[5uqq]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-Authors: Schlachter, C., Chruszcz, M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5uqq]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UQQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UQQ FirstGlance]. <br>
-Description: Crystal structure of 2-methylcitrate synthase from Aspergillus fumigatus
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SRT:S,R+MESO-TARTARIC+ACID'>SRT</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5uqo|5uqo]], [[5uqs|5uqs]], [[5uqr|5uqr]], [[5uqu|5uqu]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uqq OCA], [http://pdbe.org/5uqq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uqq RCSB], [http://www.ebi.ac.uk/pdbsum/5uqq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uqq ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/PRPC_ASPFM PRPC_ASPFM]] Component of the methylcitrate cycle that catalyzes the synthesis of (2S,3S)-2-methylcitrate from propionyl-CoA and oxaloacetate. Plays an important role in detoxification of propionyl-CoA, an inhibitor of both primary and secondary metabolism. Has also citrate synthase activity using as substrates acetyl-CoA and oxaloacetate. May play a role in virulence.<ref>PMID:16008561</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Chruszcz, M]]
 [[Category: Schlachter, C]]
+[[Category: 2-methylcitrate synthase]]
+[[Category: Citrate synthase]]
+[[Category: Mcsa]]
+[[Category: Transferase]]