2x2l: Difference between revisions

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==CRYSTAL STRUCTURE OF PHOSPHORYLATED RET TYROSINE KINASE DOMAIN WITH INHIBITOR==
 
==Crystal Structure of phosphorylated RET tyrosine kinase domain with inhibitor==
<StructureSection load='2x2l' size='340' side='right' caption='[[2x2l]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2x2l' size='340' side='right' caption='[[2x2l]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ivu|2ivu]], [[2ivt|2ivt]], [[2ivv|2ivv]], [[2ivs|2ivs]], [[2x2m|2x2m]], [[2x2k|2x2k]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ivu|2ivu]], [[2ivt|2ivt]], [[2ivv|2ivv]], [[2ivs|2ivs]], [[2x2m|2x2m]], [[2x2k|2x2k]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x2l OCA], [http://pdbe.org/2x2l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x2l RCSB], [http://www.ebi.ac.uk/pdbsum/2x2l PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x2l OCA], [http://pdbe.org/2x2l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x2l RCSB], [http://www.ebi.ac.uk/pdbsum/2x2l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x2l ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x2/2x2l_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x2/2x2l_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Kjaer, S]]
[[Category: Kjaer, S]]
[[Category: Knowles, P P]]
[[Category: Knowles, P P]]
[[Category: Mcdonald, N Q]]
[[Category: McDonald, N Q]]
[[Category: Murray-Rust, J]]
[[Category: Murray-Rust, J]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]

Revision as of 07:00, 28 February 2018

Crystal Structure of phosphorylated RET tyrosine kinase domain with inhibitor

2x2l, resolution 2.00Å

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