6flp: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6flp is ~~ON HOLD until Paper Publication~~

==CryoEM structure of E.coli RNA polymerase paused elongation complex without RNA hairpin bound to NusA==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6flp]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FLP OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FLP FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6flp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6flp OCA], [http://pdbe.org/6flp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6flp RCSB], [http://www.ebi.ac.uk/pdbsum/6flp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6flp ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/RPOZ_ECOLI RPOZ_ECOLI]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.[HAMAP-Rule:MF_00366] [[http://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059] [[http://www.uniprot.org/uniprot/RPOC_ECOLI RPOC_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01322] [[http://www.uniprot.org/uniprot/RPOB_ECOLI RPOB_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01321]

__TOC__

</StructureSection>

[[Category: DNA-directed RNA polymerase]]

[[Category: Guo, X]]

[[Category: Weixlbaumer, A]]

[[Category: His pause]]

[[Category: Nusa]]

[[Category: Rna polymerase]]

[[Category: Transcription]]

[[Category: Transcriptional pausing]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6flp is ON HOLD  until Paper Publication
+==CryoEM structure of E.coli RNA polymerase paused elongation complex without RNA hairpin bound to NusA==
+<StructureSection load='6flp' size='340' side='right' caption='[[6flp]], [[Resolution|resolution]] 4.10&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6flp]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FLP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FLP FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6flp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6flp OCA], [http://pdbe.org/6flp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6flp RCSB], [http://www.ebi.ac.uk/pdbsum/6flp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6flp ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/RPOZ_ECOLI RPOZ_ECOLI]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.[HAMAP-Rule:MF_00366] [[http://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059] [[http://www.uniprot.org/uniprot/RPOC_ECOLI RPOC_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01322] [[http://www.uniprot.org/uniprot/RPOB_ECOLI RPOB_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01321]
+__TOC__
+</StructureSection>
+[[Category: DNA-directed RNA polymerase]]
+[[Category: Guo, X]]
+[[Category: Weixlbaumer, A]]
+[[Category: His pause]]
+[[Category: Nusa]]
+[[Category: Rna polymerase]]
+[[Category: Transcription]]
+[[Category: Transcriptional pausing]]