6b3t: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 6b3t is ON HOLD~~

==Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with a 1,2,4-triazino[5,6b]indole-3-thioether inhibitor analogue 39b==

~~Authors: Gajadeera, C.S., Hou, C., Garneau-Tsodikova, S., Ngo, H.X., Tsodikov, O.V.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[6b3t]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B3T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B3T FirstGlance]. <br>

~~Description:~~ Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with a 1,2,4-triazino[5,6b]indole-3-thioether inhibitor analogue 39b

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CJ7:8-fluoro-5-methyl-3-{[2-(piperidin-1-yl)ethyl]sulfanyl}-5H-[1,2,4]triazino[5,6-b]indole'>CJ7</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b3t OCA], [http://pdbe.org/6b3t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b3t RCSB], [http://www.ebi.ac.uk/pdbsum/6b3t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b3t ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/EIS_MYCTU EIS_MYCTU]] May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.<ref>PMID:10629183</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Gajadeera, C S]]

[[Category: Garneau-Tsodikova, S]]

~~[[Category: Ngo, H.X]]~~

~~[[Category: Tsodikov, O.V]]~~

~~[[Category: Gajadeera, C.S]]~~

[[Category: Hou, C]]

[[Category: Ngo, H X]]

[[Category: Tsodikov, O V]]

[[Category: Aminoglycoside]]

[[Category: Resistance]]

[[Category: Transferase]]

[[Category: Transferase-transferase inhibitor complex]]

[[Category: Tuberculosis]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6b3t is ON HOLD
+==Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with a 1,2,4-triazino[5,6b]indole-3-thioether inhibitor analogue 39b==
+<StructureSection load='6b3t' size='340' side='right' caption='[[6b3t]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-Authors: Gajadeera, C.S., Hou, C., Garneau-Tsodikova, S., Ngo, H.X., Tsodikov, O.V.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6b3t]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B3T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B3T FirstGlance]. <br>
-Description: Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with a 1,2,4-triazino[5,6b]indole-3-thioether inhibitor analogue 39b
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CJ7:8-fluoro-5-methyl-3-{[2-(piperidin-1-yl)ethyl]sulfanyl}-5H-[1,2,4]triazino[5,6-b]indole'>CJ7</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b3t OCA], [http://pdbe.org/6b3t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b3t RCSB], [http://www.ebi.ac.uk/pdbsum/6b3t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b3t ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/EIS_MYCTU EIS_MYCTU]] May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.<ref>PMID:10629183</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Gajadeera, C S]]
 [[Category: Garneau-Tsodikova, S]]
-[[Category: Ngo, H.X]]
-[[Category: Tsodikov, O.V]]
-[[Category: Gajadeera, C.S]]
 [[Category: Hou, C]]
+[[Category: Ngo, H X]]
+[[Category: Tsodikov, O V]]
+[[Category: Aminoglycoside]]
+[[Category: Resistance]]
+[[Category: Transferase]]
+[[Category: Transferase-transferase inhibitor complex]]
+[[Category: Tuberculosis]]