Vpr protein: Difference between revisions
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<StructureSection load=' | <StructureSection load='1m8l' size='300' side='right' caption='NMR structure of the HIV-1 Regulatory Protein Vpr' scene=''> | ||
== Function == | == Function == | ||
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== Conservation == | == Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Vpr is highly conserved in HIV and simian immunodeficiency virus (SIV), similar retrovirus which infects non-human primates<ref name='Morellet2003'/>. In addition, all primate lentiviruses has vpr gene whose protein product has highly conserved motifs. HIV-2 and SIVsm lentiviruses have additionally gene - vpx. In these lentiviruses, vpr and vpx executes together the roles which HIV-1 vpr perform. Vpr and Vpx has low conservation between them. | Vpr is highly conserved in HIV and simian immunodeficiency virus (SIV), similar retrovirus which infects non-human primates<ref name='Morellet2003'/>. In addition, all primate lentiviruses has vpr gene whose protein product has highly conserved motifs. HIV-2 and SIVsm lentiviruses have additionally gene - vpx. In these lentiviruses, vpr and vpx executes together the roles which HIV-1 vpr perform. Vpr and Vpx has low conservation between them. | ||
