5oi7: Difference between revisions
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==Human CEP85 - coiled coil domain 4== | |||
<StructureSection load='5oi7' size='340' side='right' caption='[[5oi7]], [[Resolution|resolution]] 1.67Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5oi7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OI7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OI7 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oi7 OCA], [http://pdbe.org/5oi7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oi7 RCSB], [http://www.ebi.ac.uk/pdbsum/5oi7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oi7 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CEP85_HUMAN CEP85_HUMAN]] Acts as a negative regulator of NEK2 to maintain the centrosome integrity in interphase. Suppresses centrosome disjunction by inhibiting NEK2 kinase activity (PubMed:26220856).<ref>PMID:26220856</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Breugel, M van]] | |||
[[Category: Centriole]] | |||
[[Category: Centrosome]] | |||
[[Category: Cep85]] | |||
[[Category: Protein binding]] | |||
[[Category: Stil]] | |||
Revision as of 05:37, 18 April 2018
Human CEP85 - coiled coil domain 4
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