Sandbox Reserved 1453: Difference between revisions
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==Acetylcholine receptor and its reaction to cobra venom == | ==Acetylcholine receptor and its reaction to cobra venom == | ||
==Structure== | ==Structure== | ||
The acetylcholine receptor is composed of five alpha helical chains each with about 370 amino acids. This is a transmembrane protein forming a funnel into the cytosol of the cell. Alpha and beta receptors | The acetylcholine receptor is composed of five alpha helical chains each with about 370 amino acids. This is a transmembrane protein forming a funnel into the cytosol of the cell. Alpha and beta receptors | ||
<scene name='77/778333/Acetylcholine/5'>Acetylcholine Receptor</scene> | <scene name='77/778333/Acetylcholine/5'>Acetylcholine Receptor</scene> | ||
== Function as a Signal Molecule Receptor == | == Function as a Signal Molecule Receptor == | ||
The neurotransmitter acetylcholine is released into the synaptic cleft and is bound to the acetylcholine receptor. Consequently, the receptor changes conformation to release potassium ions into the cytoplasm of the cell while sodium ions are ejected from the cell through the receptor acting as an ion-gated channel. This change in ion concentration causes a change in the membrane potential of the cell. The release of sodium into extracellular matrix causes a release of more acetylcholine in a neighboring cell continuing the action potential across nerve cells. Nerve cell communication is also in control of muscle contraction. When the action potential traveling down the nerve cell reaches muscle tissue, the muscle cell responds by triggering a release in calcium to allow for muscle contraction for the organism to move. | The neurotransmitter acetylcholine is released into the synaptic cleft and is bound to the acetylcholine receptor. Consequently, the receptor changes conformation to release potassium ions into the cytoplasm of the cell while sodium ions are ejected from the cell through the receptor acting as an ion-gated channel. This change in ion concentration causes a change in the membrane potential of the cell. The release of sodium into extracellular matrix causes a release of more acetylcholine in a neighboring cell continuing the action potential across nerve cells. Nerve cell communication is also in control of muscle contraction. When the action potential traveling down the nerve cell reaches muscle tissue, the muscle cell responds by triggering a release in calcium to allow for muscle contraction for the organism to move. | ||
