2j10: Difference between revisions
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== | |||
==p53 tetramerization domain mutant T329F Q331K== | |||
<StructureSection load='2j10' size='340' side='right' caption='[[2j10]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''> | <StructureSection load='2j10' size='340' side='right' caption='[[2j10]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2j10]] is a 4 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J10 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J10 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2j10]] is a 4 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J10 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J10 FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a1u|1a1u]], [[1aie|1aie]], [[1c26|1c26]], [[1dt7|1dt7]], [[1gzh|1gzh]], [[1h26|1h26]], [[1hs5|1hs5]], [[1jsp|1jsp]], [[1kzy|1kzy]], [[1ma3|1ma3]], [[1olg|1olg]], [[1olh|1olh]], [[1pes|1pes]], [[1pet|1pet]], [[1sae|1sae]], [[1saf|1saf]], [[1sag|1sag]], [[1sah|1sah]], [[1sai|1sai]], [[1saj|1saj]], [[1sak|1sak]], [[1sal|1sal]], [[1tsr|1tsr]], [[1tup|1tup]], [[1uol|1uol]], [[1xqh|1xqh]], [[1ycq|1ycq]], [[1ycr|1ycr]], [[1ycs|1ycs]], [[2ac0|2ac0]], [[2ady|2ady]], [[2ahi|2ahi]], [[2ata|2ata]], [[2b3g|2b3g]], [[2bim|2bim]], [[2bin|2bin]], [[2bio|2bio]], [[2bip|2bip]], [[2biq|2biq]], [[2f1x|2f1x]], [[2fej|2fej]], [[2j0z|2j0z]], [[2j11|2j11]], [[3sak|3sak]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a1u|1a1u]], [[1aie|1aie]], [[1c26|1c26]], [[1dt7|1dt7]], [[1gzh|1gzh]], [[1h26|1h26]], [[1hs5|1hs5]], [[1jsp|1jsp]], [[1kzy|1kzy]], [[1ma3|1ma3]], [[1olg|1olg]], [[1olh|1olh]], [[1pes|1pes]], [[1pet|1pet]], [[1sae|1sae]], [[1saf|1saf]], [[1sag|1sag]], [[1sah|1sah]], [[1sai|1sai]], [[1saj|1saj]], [[1sak|1sak]], [[1sal|1sal]], [[1tsr|1tsr]], [[1tup|1tup]], [[1uol|1uol]], [[1xqh|1xqh]], [[1ycq|1ycq]], [[1ycr|1ycr]], [[1ycs|1ycs]], [[2ac0|2ac0]], [[2ady|2ady]], [[2ahi|2ahi]], [[2ata|2ata]], [[2b3g|2b3g]], [[2bim|2bim]], [[2bin|2bin]], [[2bio|2bio]], [[2bip|2bip]], [[2biq|2biq]], [[2f1x|2f1x]], [[2fej|2fej]], [[2j0z|2j0z]], [[2j11|2j11]], [[3sak|3sak]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j10 OCA], [http://pdbe.org/2j10 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j10 RCSB], [http://www.ebi.ac.uk/pdbsum/2j10 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j10 OCA], [http://pdbe.org/2j10 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j10 RCSB], [http://www.ebi.ac.uk/pdbsum/2j10 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2j10 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j1/2j10_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j1/2j10_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2j10 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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[[Category: Perez-Paya, E]] | [[Category: Perez-Paya, E]] | ||
[[Category: Pineda-Lucena, A]] | [[Category: Pineda-Lucena, A]] | ||
[[Category: Pino, M M.Sanchez | [[Category: Pino, M M.Sanchez del]] | ||
[[Category: Acetylation]] | |||
[[Category: Activator]] | [[Category: Activator]] | ||
[[Category: Alternative splicing]] | |||
[[Category: Anti-oncogene]] | [[Category: Anti-oncogene]] | ||
[[Category: Apoptosis]] | [[Category: Apoptosis]] | ||
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[[Category: P53]] | [[Category: P53]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
[[Category: Polymorphism]] | |||
[[Category: Tetramerization domain]] | [[Category: Tetramerization domain]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
[[Category: Wild type]] | [[Category: Wild type]] | ||
[[Category: Zinc]] | |||
