Sandbox GGC10: Difference between revisions
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<StructureSection load='1psn' size='350' side='right' caption='Human Pepsin' scene=" > | <StructureSection load='1psn' size='350' side='right' caption='Human Pepsin' scene=" > | ||
Pepsin is considered a powerful enzyme found in the stomach of humans and other animals. It helps breakdown and digest proteins into small peptides like meat, seeds, eggs, or dairy products. It is produced by the human gastric mucosa. Pepsin is in complex with pepstatin. It is a very important enzyme, hence one of the first enzymes to be discovered. | Pepsin is considered a powerful enzyme found in the stomach of humans and other animals. It helps breakdown and digest proteins into small peptides like meat, seeds, eggs, or dairy products. It is produced by the human gastric mucosa. Pepsin is in complex with pepstatin. It is a very important enzyme, hence one of the first enzymes to be discovered. | ||
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<scene name='75/752264/Residues/1'>The structure of Human Pepsin is similar to a serine Endoproteinase with molecular weight of 35 kd. the structure is divided into 3 domains. The main domain includes 6 stranded antiparallel beta sheet that helps as a backbone to the active site region. It is comprised of residues Val 1- Leu 6, Asp 149- Val 184, and Gln 308-Ala 326. The N-terminal is also composed of residues | <scene name='75/752264/Residues/1'>The structure of Human Pepsin is similar to a serine Endoproteinase with molecular weight of 35 kd. the structure is divided into 3 domains. The main domain includes 6 stranded antiparallel beta sheet that helps as a backbone to the active site region. It is comprised of residues Val 1- Leu 6, Asp 149- Val 184, and Gln 308-Ala 326. The N-terminal is also composed of residues | ||
<scene name='75/752264/Pepstatin/1'>The region of the pepstatin molecule the residues shown. Ala,Iva, and residues as well as Sta terminal are low on density. They have generate new conformations since the model can't fit</scene> | |||
<scene name='75/752264/Pepstatin/1'></scene> | |||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
https://onlinelibrary.wiley.com/doi/epdf/10.1002/pro.5560040516?referrer_access_token=ZyEVxvIcTcmK5L-vwA_P2k4keas67K9QMdWULTWMo8PQPfTnSk44hq4jBFsrHa9ydjFbMYZrHWbY_9SWvlJek7YeLttGlVWslX2Nvc9rYhwoytl58c9enHGXzQqZutfC | https://onlinelibrary.wiley.com/doi/epdf/10.1002/pro.5560040516?referrer_access_token=ZyEVxvIcTcmK5L-vwA_P2k4keas67K9QMdWULTWMo8PQPfTnSk44hq4jBFsrHa9ydjFbMYZrHWbY_9SWvlJek7YeLttGlVWslX2Nvc9rYhwoytl58c9enHGXzQqZutfC | ||
