6d47: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 6d47 is ON HOLD~~

==Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Mycobacterium marinum==

~~Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)~~

== Structural highlights ==

<table><tr><td colspan='2'>[[6d47]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D47 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D47 FirstGlance]. <br>

~~Description:~~ Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Mycobacterium marinum

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d47 OCA], [http://pdbe.org/6d47 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d47 RCSB], [http://www.ebi.ac.uk/pdbsum/6d47 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d47 ProSAT]</span></td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

[[Category: ~~Seattle Structural Genomics Center For Infectious Disease (~~Ssgcid)]]

== Function ==

[[http://www.uniprot.org/uniprot/B2HI47_MYCMM B2HI47_MYCMM]] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[PIRNR:PIRNR000804]

__TOC__

</StructureSection>

[[Category: Structural genomic]]

[[Category: Dna binding protein]]

[[Category: Griselimycin]]

[[Category: Mtb]]

[[Category: National institute of allergy and infectious disease]]

[[Category: Niaid]]

[[Category: Ssgcid]]

[[Category: Tuberculosis]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6d47 is ON HOLD
+==Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Mycobacterium marinum==
+<StructureSection load='6d47' size='340' side='right' caption='[[6d47]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
-Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6d47]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D47 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D47 FirstGlance]. <br>
-Description: Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Mycobacterium marinum
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d47 OCA], [http://pdbe.org/6d47 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d47 RCSB], [http://www.ebi.ac.uk/pdbsum/6d47 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d47 ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Seattle Structural Genomics Center For Infectious Disease (Ssgcid)]]
+== Function ==
+[[http://www.uniprot.org/uniprot/B2HI47_MYCMM B2HI47_MYCMM]] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[PIRNR:PIRNR000804]
+__TOC__
+</StructureSection>
+[[Category: Structural genomic]]
+[[Category: Dna binding protein]]
+[[Category: Griselimycin]]
+[[Category: Mtb]]
+[[Category: National institute of allergy and infectious disease]]
+[[Category: Niaid]]
+[[Category: Ssgcid]]
+[[Category: Tuberculosis]]