2cn5: Difference between revisions
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== | |||
==Crystal structure of human Chk2 in complex with ADP== | |||
<StructureSection load='2cn5' size='340' side='right' caption='[[2cn5]], [[Resolution|resolution]] 2.25Å' scene=''> | <StructureSection load='2cn5' size='340' side='right' caption='[[2cn5]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gxc|1gxc]], [[2cn8|2cn8]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gxc|1gxc]], [[2cn8|2cn8]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cn5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cn5 OCA], [http://pdbe.org/2cn5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cn5 RCSB], [http://www.ebi.ac.uk/pdbsum/2cn5 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cn5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cn5 OCA], [http://pdbe.org/2cn5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cn5 RCSB], [http://www.ebi.ac.uk/pdbsum/2cn5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cn5 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cn/2cn5_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cn/2cn5_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cn5 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
Revision as of 08:01, 23 May 2018
Crystal structure of human Chk2 in complex with ADP
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Human
- Non-specific serine/threonine protein kinase
- Oliver, A W
- Pearl, L H
- Activation segment
- Atp-binding
- Cancer
- Cds1
- Cell cycle
- Checkpoint
- Chek2
- Chk2
- Disease mutation
- Kinase
- Kinase domain
- Li-fraumeni syndrome
- Magnesium
- Metal-binding
- Nuclear protein
- Nucleotide-binding
- Phosphorylation
- Proto-oncogene
- Rad53
- Serine/threonine-protein kinase
- Transferase
- Tumour suppressor
