User:Luis Netto/Sandbox 1: Difference between revisions

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 == Disease ==
+related with relevance
 == Relevance ==
+Oxidants such as fatty acid hydroperoxides are signaling molecules involved in host-pathogen
+interactions, and therefore, their levels are strictly controlled by peroxidases and other mechanisms
+[1±4]. Ohr (Organic hydroperoxide resistance) proteins are Cys-based, dithiol-dependent
+peroxidases that display unique biochemical and structural properties [5,6]. Ohr enzymes
+play central roles in the bacterial response to peroxynitrite and fatty acid hydroperoxides, two
+oxidants involved in host±pathogen interactions [1]. These enzymes are found in bacteria and
+fungi, and they are absent in their hosts (plants and animals) [7], making them promising targets
+for drug discovery. Some examples of pathogenic bacteria that express Ohr proteins are
+Pseudomonas aeruginosa, Vibrio cholerae and Xyllela fastidiosa [7]. Xylella fastidiosa is a plant
+pathogen with agronomic interest, causing disease in citrus, grapes and olives [8].
 == Structural highlights ==

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