6f62: Difference between revisions
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==Crystal structure of the SYCP1 N-terminal head-to-head assembly in open conformation== | |||
<StructureSection load='6f62' size='340' side='right' caption='[[6f62]], [[Resolution|resolution]] 2.07Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6f62]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F62 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F62 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr> | |||
[[ | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6f5x|6f5x]]</td></tr> | ||
[[Category: Davies, O | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f62 OCA], [http://pdbe.org/6f62 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f62 RCSB], [http://www.ebi.ac.uk/pdbsum/6f62 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f62 ProSAT]</span></td></tr> | ||
[[Category: Dunce, J | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/SYCP1_HUMAN SYCP1_HUMAN]] Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility.[UniProtKB:Q62209] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Davies, O R]] | |||
[[Category: Dunce, J M]] | |||
[[Category: Chromosome structure]] | |||
[[Category: Coiled-coil]] | |||
[[Category: Meiosis]] | |||
[[Category: Self-assembly]] | |||
[[Category: Structural protein]] | |||
Revision as of 06:00, 6 June 2018
Crystal structure of the SYCP1 N-terminal head-to-head assembly in open conformation
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