6dk3: Difference between revisions
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==HUMAN MITOCHONDRIAL SERINE HYDROXYMETHYLTRANSFERASe 2== | |||
<StructureSection load='6dk3' size='340' side='right' caption='[[6dk3]], [[Resolution|resolution]] 2.04Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6dk3]] is a 1 chain structure. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3ou5 3ou5] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2a7v 2a7v]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DK3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DK3 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycine_hydroxymethyltransferase Glycine hydroxymethyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.1 2.1.2.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dk3 OCA], [http://pdbe.org/6dk3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dk3 RCSB], [http://www.ebi.ac.uk/pdbsum/6dk3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dk3 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/GLYM_HUMAN GLYM_HUMAN]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA.<ref>PMID:21876188</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Glycine hydroxymethyltransferase]] | |||
[[Category: Arrowsmith, C H]] | |||
[[Category: Bochkarev, A]] | |||
[[Category: Dong, A]] | |||
[[Category: Edwards, A M]] | |||
[[Category: Loppnau, P]] | [[Category: Loppnau, P]] | ||
[[Category: Plotnikov, A | [[Category: Plotnikov, A N]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Sundstrom, M]] | [[Category: Sundstrom, M]] | ||
[[Category: | [[Category: Wu, H]] | ||
[[Category: Zeng, H]] | [[Category: Zeng, H]] | ||
[[Category: | [[Category: Sgc]] | ||
[[Category: Shmt2]] | |||
[[Category: Transferase]] | |||