6dk3: Difference between revisions

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'''Unreleased structure'''


The entry 6dk3 is ON HOLD
==HUMAN MITOCHONDRIAL SERINE HYDROXYMETHYLTRANSFERASe 2==
 
<StructureSection load='6dk3' size='340' side='right' caption='[[6dk3]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
Authors: Dong, A., Wu, H., Zeng, H., Loppnau, P., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6dk3]] is a 1 chain structure. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3ou5 3ou5] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2a7v 2a7v]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DK3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DK3 FirstGlance]. <br>
Description: HUMAN MITOCHONDRIAL SERINE HYDROXYMETHYLTRANSFERASe 2
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycine_hydroxymethyltransferase Glycine hydroxymethyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.1 2.1.2.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dk3 OCA], [http://pdbe.org/6dk3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dk3 RCSB], [http://www.ebi.ac.uk/pdbsum/6dk3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dk3 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/GLYM_HUMAN GLYM_HUMAN]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA.<ref>PMID:21876188</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Glycine hydroxymethyltransferase]]
[[Category: Arrowsmith, C H]]
[[Category: Bochkarev, A]]
[[Category: Dong, A]]
[[Category: Edwards, A M]]
[[Category: Loppnau, P]]
[[Category: Loppnau, P]]
[[Category: Plotnikov, A.N]]
[[Category: Plotnikov, A N]]
[[Category: Edwards, A.M]]
[[Category: Structural genomic]]
[[Category: Arrowsmith, C.H]]
[[Category: Sundstrom, M]]
[[Category: Sundstrom, M]]
[[Category: Dong, A]]
[[Category: Wu, H]]
[[Category: Structural Genomics Consortium (Sgc)]]
[[Category: Bochkarev, A]]
[[Category: Zeng, H]]
[[Category: Zeng, H]]
[[Category: Wu, H]]
[[Category: Sgc]]
[[Category: Shmt2]]
[[Category: Transferase]]