2j7t: Difference between revisions
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== | |||
==Crystal structure of human serine threonine kinase-10 bound to SU11274== | |||
<StructureSection load='2j7t' size='340' side='right' caption='[[2j7t]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='2j7t' size='340' side='right' caption='[[2j7t]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=274:(3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-1H-PYRROL-2-YL}METHYLENE)-N-METHYL-2-OXOINDOLINE-5-SULFONAMIDE'>274</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=274:(3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-1H-PYRROL-2-YL}METHYLENE)-N-METHYL-2-OXOINDOLINE-5-SULFONAMIDE'>274</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j7t OCA], [http://pdbe.org/2j7t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j7t RCSB], [http://www.ebi.ac.uk/pdbsum/2j7t PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j7t OCA], [http://pdbe.org/2j7t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j7t RCSB], [http://www.ebi.ac.uk/pdbsum/2j7t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2j7t ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j7/2j7t_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j7/2j7t_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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[[Category: Das, S]] | [[Category: Das, S]] | ||
[[Category: Debreczeni, J]] | [[Category: Debreczeni, J]] | ||
[[Category: Delft, F | [[Category: Delft, F von]] | ||
[[Category: Edwards, A]] | [[Category: Edwards, A]] | ||
[[Category: Eswaran, J]] | [[Category: Eswaran, J]] | ||
Revision as of 05:44, 27 June 2018
Crystal structure of human serine threonine kinase-10 bound to SU11274
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Human
- Non-specific serine/threonine protein kinase
- Arrowsmith, C H
- Das, S
- Debreczeni, J
- Delft, F von
- Edwards, A
- Eswaran, J
- Fedorov, O
- Gorrec, F
- Knapp, S
- Papagrigoriou, E
- Pike, A C.W
- Rellos, P
- Savitsky, P
- Sobott, F
- Sundstrom, M
- Turnbull, A P
- Ugochukwa, E
- Umeano, C C
- Watt, S
- Weigelt, J
- Atp-binding
- Cell cycle progression
- Disease mutation
- Kinase
- Nucleotide- binding
- Phosphorylation
- Serine/threonine- protein kinase
- Transferase
