2nt1: Difference between revisions

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|PDB= 2nt1 |SIZE=350|CAPTION= <scene name='initialview01'>2nt1</scene>, resolution 2.300&Aring;
|PDB= 2nt1 |SIZE=350|CAPTION= <scene name='initialview01'>2nt1</scene>, resolution 2.300&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene> and <scene name='pdbligand=PO4:PHOSPHATE ION'>PO4</scene>
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Glucosylceramidase Glucosylceramidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.45 3.2.1.45]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucosylceramidase Glucosylceramidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.45 3.2.1.45] </span>
|GENE= GBA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= GBA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[2nsx|2NSX]], [[2nt0|2NT0]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nt1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nt1 OCA], [http://www.ebi.ac.uk/pdbsum/2nt1 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2nt1 RCSB]</span>
}}
}}


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==Disease==
==Disease==
Known diseases associated with this structure: Gaucher disease, perinatal lethal OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606463 606463]], Gaucher disease, type I OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606463 606463]], Gaucher disease, type II OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606463 606463]], Gaucher disease, type III OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606463 606463]], Gaucher disease, type IIIC OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606463 606463]], Graves disease, susceptibility to, 3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=139200 139200]]
Known disease associated with this structure: Gaucher disease, perinatal lethal OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606463 606463]], Gaucher disease, type I OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606463 606463]], Gaucher disease, type II OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606463 606463]], Gaucher disease, type III OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606463 606463]], Gaucher disease, type IIIC OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606463 606463]]


==About this Structure==
==About this Structure==
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[[Category: Petsko, G A.]]
[[Category: Petsko, G A.]]
[[Category: Ringe, D.]]
[[Category: Ringe, D.]]
[[Category: NAG]]
[[Category: PO4]]
[[Category: acid-beta-glucosidase]]
[[Category: acid-beta-glucosidase]]
[[Category: cerezyme]]
[[Category: cerezyme]]
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[[Category: glucosylceramide]]
[[Category: glucosylceramide]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:50:46 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:07:58 2008''