2j1w: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
== | |||
==Human p53 core domain mutant M133L-V143A-V203A-N239Y-N268D== | |||
<StructureSection load='2j1w' size='340' side='right' caption='[[2j1w]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='2j1w' size='340' side='right' caption='[[2j1w]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| Line 5: | Line 6: | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hu8|1hu8]], [[1uol|1uol]], [[2bim|2bim]], [[2bin|2bin]], [[2bio|2bio]], [[2bip|2bip]], [[2biq|2biq]], [[2j1x|2j1x]], [[2j1y|2j1y]], [[2j1z|2j1z]], [[2j20|2j20]], [[2j21|2j21]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hu8|1hu8]], [[1uol|1uol]], [[2bim|2bim]], [[2bin|2bin]], [[2bio|2bio]], [[2bip|2bip]], [[2biq|2biq]], [[2j1x|2j1x]], [[2j1y|2j1y]], [[2j1z|2j1z]], [[2j20|2j20]], [[2j21|2j21]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j1w OCA], [http://pdbe.org/2j1w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j1w RCSB], [http://www.ebi.ac.uk/pdbsum/2j1w PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j1w OCA], [http://pdbe.org/2j1w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j1w RCSB], [http://www.ebi.ac.uk/pdbsum/2j1w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2j1w ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
| Line 15: | Line 16: | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j1/2j1w_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j1/2j1w_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 40: | Line 41: | ||
[[Category: Fersht, A R]] | [[Category: Fersht, A R]] | ||
[[Category: Joerger, A C]] | [[Category: Joerger, A C]] | ||
[[Category: Acetylation]] | |||
[[Category: Activator]] | [[Category: Activator]] | ||
[[Category: Alternative splicing]] | |||
[[Category: Anti-oncogene]] | [[Category: Anti-oncogene]] | ||
[[Category: Apoptosis]] | [[Category: Apoptosis]] | ||
| Line 55: | Line 58: | ||
[[Category: P53 dna-binding domain]] | [[Category: P53 dna-binding domain]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
[[Category: Polymorphism]] | |||
[[Category: Second-site suppressor mutation]] | [[Category: Second-site suppressor mutation]] | ||
[[Category: Superstable mutant]] | [[Category: Superstable mutant]] | ||
| Line 61: | Line 65: | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Tumor suppressor]] | [[Category: Tumor suppressor]] | ||
[[Category: Zinc]] | |||
