5qih: Difference between revisions

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'''Unreleased structure'''


The entry 5qih is ON HOLD
==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of HAO1 in complex with Z2697514548==
 
<StructureSection load='5qih' size='340' side='right' caption='[[5qih]], [[Resolution|resolution]] 1.33&Aring;' scene=''>
Authors: MacKinnon, S., Bezerra, G.A., Krojer, T., Bradley, A.R., Talon, R., Brandao-Neto, J., Douangamath, A., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Oppermann, U., Brennan, P.E., Yue, W.W.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5qih]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QIH FirstGlance]. <br>
Description: PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) --Crystal Structure of HAO1 in complex with Z2697514548
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GWG:1-methylindazole-3-carboxamide'>GWG</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-2-hydroxy-acid_oxidase (S)-2-hydroxy-acid oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.15 1.1.3.15] </span></td></tr>
[[Category: Mackinnon, S]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qih OCA], [http://pdbe.org/5qih PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qih RCSB], [http://www.ebi.ac.uk/pdbsum/5qih PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qih ProSAT]</span></td></tr>
[[Category: Bradley, A.R]]
</table>
[[Category: Arrowsmith, C.H]]
== Function ==
[[http://www.uniprot.org/uniprot/HAOX1_HUMAN HAOX1_HUMAN]] Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate.
__TOC__
</StructureSection>
[[Category: Arrowsmith, C H]]
[[Category: Bezerra, G A]]
[[Category: Bountra, C]]
[[Category: Bradley, A R]]
[[Category: Brandao-Neto, J]]
[[Category: Brandao-Neto, J]]
[[Category: Talon, R]]
[[Category: Brennan, P E]]
[[Category: Brennan, P.E]]
[[Category: Delft, F von]]
[[Category: Oppermann, U]]
[[Category: Douangamath, A]]
[[Category: Bezerra, G.A]]
[[Category: Edwards, A]]
[[Category: Edwards, A]]
[[Category: Douangamath, A]]
[[Category: Krojer, T]]
[[Category: Krojer, T]]
[[Category: Yue, W.W]]
[[Category: MacKinnon, S]]
[[Category: Von Delft, F]]
[[Category: Oppermann, U]]
[[Category: Bountra, C]]
[[Category: Talon, R]]
[[Category: Yue, W W]]
[[Category: Hao1]]
[[Category: Oxidoreductase]]
[[Category: Pandda]]
[[Category: Sgc - diamond i04-1 fragment screening]]
[[Category: Xchemexplorer]]
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