6gy4: Difference between revisions

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'''Unreleased structure'''


The entry 6gy4 is ON HOLD
==Crystal structure of the N-terminal KH domain of human BICC1==
 
<StructureSection load='6gy4' size='340' side='right' caption='[[6gy4]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
Authors: Newman, J.A., Katis, V.L., Shrestha, L., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6gy4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GY4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GY4 FirstGlance]. <br>
Description: Crystal structure of the N-terminal KH domain of human BICC1
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XPE:3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL'>XPE</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gy4 OCA], [http://pdbe.org/6gy4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gy4 RCSB], [http://www.ebi.ac.uk/pdbsum/6gy4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gy4 ProSAT]</span></td></tr>
[[Category: Katis, V.L]]
</table>
[[Category: Arrowsmith, C.H]]
== Disease ==
[[http://www.uniprot.org/uniprot/BICC1_HUMAN BICC1_HUMAN]] Autosomal dominant polycystic kidney disease. Disease susceptibility is associated with variations affecting the gene represented in this entry.
== Function ==
[[http://www.uniprot.org/uniprot/BICC1_HUMAN BICC1_HUMAN]] Putative RNA-binding protein. Acts as a negative regulator of Wnt signaling. May be involved in regulating gene expression during embryonic development.<ref>PMID:21922595</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Burgess-Brown, N]]
[[Category: Burgess-Brown, N]]
[[Category: Delft, F von]]
[[Category: Edwards, A]]
[[Category: Gileadi, O]]
[[Category: Katis, V L]]
[[Category: Newman, J A]]
[[Category: Shrestha, L]]
[[Category: Shrestha, L]]
[[Category: Von Delft, F]]
[[Category: Bicaudal]]
[[Category: Gileadi, O]]
[[Category: Kh domain]]
[[Category: Newman, J.A]]
[[Category: Rna binding]]
[[Category: Edwards, A]]
[[Category: Rna binding protein]]
[[Category: Bountra, C]]
[[Category: Transcription]]