Luciferase: Difference between revisions
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<StructureSection load='3iep' size='350' side='right' scene='Luciferase/Cv/1' caption='Luciferase (PDB code [[3iep]])'> | <StructureSection load='3iep' size='350' side='right' scene='Luciferase/Cv/1' caption='Luciferase (PDB code [[3iep]])'> | ||
== Function == | == Function == | ||
[[Luciferase]] (Luc) is an oxidative enzyme used in bioluminescence. It catalyzes the oxidation of the pigment luciferin producing oxyluciferin and light<ref>PMID:2030669</ref>. See detailed analysis in<br /> | [[Luciferase]] (Luc) or '''luciferin monooxygenase''' (Lucmo)is an oxidative enzyme used in bioluminescence. It catalyzes the oxidation of the pigment luciferin producing oxyluciferin and light<ref>PMID:2030669</ref>. See detailed analysis in<br /> | ||
* [[Luciola cruciata luciferase]]<br /> | * [[Luciola cruciata luciferase]]<br /> | ||
* [[Luciferase FMN complex- Vibrio harveyi]]<br /> | * [[Luciferase FMN complex- Vibrio harveyi]]<br /> | ||
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | |||
* Luciferase | |||
**[[1ba3]] – fLuc+bromoform - firefly<br /> | |||
**[[3qya]] – LtLuc (mutant) – ''Lampyris turkestanicus''<br /> | |||
**[[4m46]] – LtLuc<br /> | |||
**[[3fgc]] – VhLuc α+β chain+FMN – ''Vibrio harveyi''<br /> | |||
**[[1luc]], [[1brl]] - VhLuc α+β chain<br /> | |||
**[[1bsl]], [[1xkj]] - VhLuc β chain<br /> | |||
*Luciferin 2-monooxygenase | |||
**[[2psd]], [[2psh]], [[2psj]], [[2pse]], [[2psf]] – Luc (mutant) – ''Renilla reniformis''<br /> | |||
**[[5b0u]] – Luc2mo (mutant) catalytic subunit – luminous shrimp<br /> | |||
*Luciferin 4-monooxygenase | |||
**[[3iep]], [[1lci]], [[5dv9]], [[3ier]] – fLuc <br /> | |||
**[[5kyt]], [[5kyv]] – fLuc (mutant)<br /> | |||
**[[5dwv]] – fLuc+ substrate analog<br /> | |||
**[[3ies]], [[3rix]], [[4e5d]] – fLuc+inhibitor<br /> | |||
**[[4g36]] – fLUc + dehydroluciferyl-sulfamoyl adenosine<br /> | |||
**[[4g37]] – fLUc (mutant) + dehydroluciferyl-sulfamoyl adenosine<br /> | |||
**[[5gz2]] – fLuc + thiazole derivative<br /> | |||
**[[5gyz]] – fLuc + AMP + thiazole derivative<br /> | |||
**[[5wys]] – fLuc + inhibitor<br /> | |||
**[[2d1q]] – LcLuc (mutant)+MgATP – ''Luciola cruciata''<br /> | |||
**[[2d1r]] - LcLuc (mutant)+oxyluciferin+AMP<br /> | |||
**[[2d1s]], [[2d1t]] - LcLuc (mutant)+intermediate analog<br /> | |||
**[[2psd]], [[2psh]], [[2psj]], [[2pse]], [[2psf]] – Luc (mutant) – ''Renilla reniformis''<br /> | |||
}} | |||
