5y2i: Difference between revisions
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==Phosphoglycerate mutase 1 (PGAM1) complexed with its inhibitor PGMI-004A== | |||
<StructureSection load='5y2i' size='340' side='right' caption='[[5y2i]], [[Resolution|resolution]] 1.92Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5y2i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y2I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Y2I FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8KX:3,4-bis(oxidanyl)-9,10-bis(oxidanylidene)-~{N}-[4-(trifluoromethyl)phenyl]anthracene-2-sulfonamide'>8KX</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5y2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y2i OCA], [http://pdbe.org/5y2i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y2i RCSB], [http://www.ebi.ac.uk/pdbsum/5y2i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y2i ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/PGAM1_HUMAN PGAM1_HUMAN]] Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Jiang, L]] | |||
[[Category: Zhou, L]] | |||
[[Category: Isomerase-inhibitor complex]] | |||
[[Category: Phosphoglycerate mutase]] | |||
Revision as of 21:41, 9 August 2018
Phosphoglycerate mutase 1 (PGAM1) complexed with its inhibitor PGMI-004A
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