6gb2: Difference between revisions
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''' | {{Large structure}} | ||
==Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the 39S ribosomal subunit.== | |||
<StructureSection load='6gb2' size='340' side='right' caption='[[6gb2]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6gb2]] is a 62 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GB2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GB2 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=FME:N-FORMYLMETHIONINE'>FME</scene>, <scene name='pdbligand=GSP:5-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE'>GSP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gb2 OCA], [http://pdbe.org/6gb2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gb2 RCSB], [http://www.ebi.ac.uk/pdbsum/6gb2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gb2 ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
{{Large structure}} | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/IF2M_HUMAN IF2M_HUMAN]] One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Sus scrofa]] | |||
[[Category: Ban, N]] | |||
[[Category: Boehringer, D]] | |||
[[Category: Kummer, E]] | |||
[[Category: Leibundgut, M]] | |||
[[Category: Initiation factor if2]] | |||
[[Category: Membrane targeting]] | |||
[[Category: Mitochondria]] | |||
[[Category: Ribosome]] | |||
[[Category: Translation initiation]] | |||