6gwr: Difference between revisions
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==Structure of the kinase domain of human DDR1 in complex with a potent and selective inhibitor of DDR1 and DDR2== | |||
<StructureSection load='6gwr' size='340' side='right' caption='[[6gwr]], [[Resolution|resolution]] 2.07Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6gwr]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GWR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GWR FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FEW:3-(2-imidazo[1,2-a]pyrazin-3-ylethynyl)-~{N}-[3-[(4-methylpiperazin-1-yl)methyl]-5-(trifluoromethyl)phenyl]-4-propan-2-yl-benzamide'>FEW</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | ||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gwr OCA], [http://pdbe.org/6gwr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gwr RCSB], [http://www.ebi.ac.uk/pdbsum/6gwr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gwr ProSAT]</span></td></tr> | ||
[[ | </table> | ||
[[ | __TOC__ | ||
[[ | </StructureSection> | ||
[[ | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: | [[Category: Arrowsmith, C H]] | ||
[[Category: | |||
[[Category: Bountra, C]] | [[Category: Bountra, C]] | ||
[[Category: Bullock, A N]] | |||
[[Category: Burgess-Brown, N A]] | |||
[[Category: Delft, F von]] | |||
[[Category: Edwards, A M]] | |||
[[Category: Fox, A E]] | |||
[[Category: Kupinska, K]] | [[Category: Kupinska, K]] | ||
[[Category: Pinkas, D M]] | |||
[[Category: Ai domain]] | |||
[[Category: Cct domain]] | |||
[[Category: Peptide binding protein]] | |||
[[Category: Rfxv motif binding]] | |||
[[Category: Wnk2]] | |||
Revision as of 21:58, 9 August 2018
Structure of the kinase domain of human DDR1 in complex with a potent and selective inhibitor of DDR1 and DDR2
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