2oxz: Difference between revisions

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|PDB= 2oxz |SIZE=350|CAPTION= <scene name='initialview01'>2oxz</scene>, resolution 1.90&Aring;
|PDB= 2oxz |SIZE=350|CAPTION= <scene name='initialview01'>2oxz</scene>, resolution 1.90&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] </span>
|GENE= MMP12, HME ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= MMP12, HME ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[2oxw|2OXW]], [[2oxu|2OXU]], [[1y93|1Y93]], [[1rmz|1RMZ]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oxz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oxz OCA], [http://www.ebi.ac.uk/pdbsum/2oxz PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2oxz RCSB]</span>
}}
}}


'''Human MMP-12 in complex with two peptides PQG and IAG'''
'''Human MMP-12 in complex with two peptides PQG and IAG'''


==Disease==
Known diseases associated with this structure: Cardiomyopathy, dilated, 1G OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=188840 188840]], Cardiomyopathy, familial hypertrophic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=188840 188840]], Muscular dystrophy, limb-girdle, type 2J OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=188840 188840]], Myopathy, early-onset, with fatal cardiomyopathy OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=188840 188840]], Myopathy, proximal, with early respiratory muscle involvement OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=188840 188840]], Tibial muscular dystrophy, tardive OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=188840 188840]]


==About this Structure==
==About this Structure==
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[[Category: Maletta, M.]]
[[Category: Maletta, M.]]
[[Category: Yeo, K J.]]
[[Category: Yeo, K J.]]
[[Category: CA]]
[[Category: ZN]]
[[Category: matrix metalloproteinase]]
[[Category: matrix metalloproteinase]]
[[Category: mmp-12]]
[[Category: mmp-12]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:24:55 2008''
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