2p8u: Difference between revisions

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|PDB= 2p8u |SIZE=350|CAPTION= <scene name='initialview01'>2p8u</scene>, resolution 2.00&Aring;
|PDB= 2p8u |SIZE=350|CAPTION= <scene name='initialview01'>2p8u</scene>, resolution 2.00&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=COA:COENZYME+A'>COA</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|LIGAND= <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SCY:S-ACETYL-CYSTEINE'>SCY</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_synthase Hydroxymethylglutaryl-CoA synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.10 2.3.3.10]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_synthase Hydroxymethylglutaryl-CoA synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.10 2.3.3.10] </span>
|GENE= HMGCS1, HMGCS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= HMGCS1, HMGCS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p8u OCA], [http://www.ebi.ac.uk/pdbsum/2p8u PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2p8u RCSB]</span>
}}
}}


'''Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I'''
'''Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I'''


==Disease==
Known disease associated with this structure: HMG-CoA synthase-2 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600234 600234]]


==About this Structure==
==About this Structure==
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[[Category: Umeano, C.]]
[[Category: Umeano, C.]]
[[Category: Weigelt, J.]]
[[Category: Weigelt, J.]]
[[Category: COA]]
[[Category: GOL]]
[[Category: hydromethylglutaryl coa]]
[[Category: hydromethylglutaryl coa]]
[[Category: mevalonate pathway]]
[[Category: mevalonate pathway]]
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[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:10:13 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:32:24 2008''
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