5nb1: Difference between revisions
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==Crystal structures of homooligomers of collagen type IV. alpha4NC1== | |||
<StructureSection load='5nb1' size='340' side='right' caption='[[5nb1]], [[Resolution|resolution]] 2.82Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5nb1]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NB1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NB1 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nb1 OCA], [http://pdbe.org/5nb1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nb1 RCSB], [http://www.ebi.ac.uk/pdbsum/5nb1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nb1 ProSAT]</span></td></tr> | |||
[[ | </table> | ||
== Disease == | |||
[[http://www.uniprot.org/uniprot/CO4A4_HUMAN CO4A4_HUMAN]] Benign familial hematuria;Autosomal dominant Alport syndrome;Autosomal recessive Alport syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CO4A4_HUMAN CO4A4_HUMAN]] Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Casino, P]] | [[Category: Casino, P]] | ||
[[Category: Marina, A]] | [[Category: Marina, A]] | ||
[[Category: Non-collagenous domain of collagen type iv. a principal structural component of basement membrane]] | |||
[[Category: Structural protein]] | |||