2pze: Difference between revisions

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|PDB= 2pze |SIZE=350|CAPTION= <scene name='initialview01'>2pze</scene>, resolution 1.700&Aring;
|PDB= 2pze |SIZE=350|CAPTION= <scene name='initialview01'>2pze</scene>, resolution 1.700&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=ATP:ADENOSINE-5&#39;-TRIPHOSPHATE'>ATP</scene>
|LIGAND= <scene name='pdbligand=ATP:ADENOSINE-5&#39;-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>
|ACTIVITY=  
|ACTIVITY=  
|GENE= CFTR, ABCC7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= CFTR, ABCC7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[1xmi|1XMI]], [[1xmj|1XMJ]], [[2bb0|2BB0]], [[2bbs|2BBS]], [[2bbt|2BBT]], [[1r0z|1R0Z]], [[1r10|1R10]], [[2ixe|2IXE]], [[1l2t|1L2T]], [[1q12|1Q12]], [[1xef|1XEF]], [[2hyd|2HYD]], [[2pzf|2PZF]], [[2pzg|2PZG]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pze OCA], [http://www.ebi.ac.uk/pdbsum/2pze PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pze RCSB]</span>
}}
}}


'''Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer'''
'''Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer'''


==Disease==
Known diseases associated with this structure: Congenital bilateral absence of vas deferens OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]], Cystic fibrosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]], Hypertrypsinemia, neonatal OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]], Pancreatitis, idiopathic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]], Sweat chloride elevation without CF OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]]


==About this Structure==
==About this Structure==
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[[Category: Wasserman, S R.]]
[[Category: Wasserman, S R.]]
[[Category: Zhao, X.]]
[[Category: Zhao, X.]]
[[Category: ATP]]
[[Category: MG]]
[[Category: abc transporter]]
[[Category: abc transporter]]
[[Category: cftr]]
[[Category: cftr]]
Line 41: Line 39:
[[Category: nbd]]
[[Category: nbd]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 15:41:51 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:42:40 2008''

Revision as of 01:42, 31 March 2008

File:2pze.gif


Drag the structure with the mouse to rotate
2pze, resolution 1.700Å
Ligands: ATP, MG
Gene: CFTR, ABCC7 (Homo sapiens)
Related: 1XMI, 1XMJ, 2BB0, 2BBS, 2BBT, 1R0Z, 1R10, 2IXE, 1L2T, 1Q12, 1XEF, 2HYD, 2PZF, 2PZG


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer


About this Structure

2PZE is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Mon Mar 31 04:42:40 2008

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