Intrinsically Disordered Protein: Difference between revisions
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Meta-servers gather the predictions from other servers into a single report. | Meta-servers gather the predictions from other servers into a single report. | ||
* [http://mobidb.bio.unipd.it/ MobiDB]. The ''Structure'' section in entries at [http://uniprot.org UniProt.Org] offers MobiDB. | * [http://mobidb.bio.unipd.it/ MobiDB]. The ''Structure'' section in entries at [http://uniprot.org UniProt.Org] offers MobiDB. MobiDB also includes manually curated disorder data along with derived and predicted data. | ||
* [http://d2p2.pro/ D<sup>2</sup>P<sup>2</sup>]: "pre-computed disorder predictions on a large library of proteins from completely-sequenced genomes. ... statistical comparisons of the various prediction methods ...." | * [http://d2p2.pro/ D<sup>2</sup>P<sup>2</sup>]: "pre-computed disorder predictions on a large library of proteins from completely-sequenced genomes. ... statistical comparisons of the various prediction methods ...." | ||
* [http://www.ideal.force.cs.is.nagoya-u.ac.jp/IDEAL/ IDEAL: Intrinsically Disordered proteins with Extensive Annotations and Literature]: " We have introduced a new category..which only has an evidence of "ordered" in a binding state, but is thought to be "disordered" in an isolated state by manual inspections and the results of several disorder-prediction tools (DICHOT, Mobi, d2p2 etc.)" | |||
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''The above list is incomplete. Addition of other servers is welcome, and summaries of methods, pros and cons for each server would be useful.'' | ''The above list is incomplete. Addition of other servers is welcome, and summaries of methods, pros and cons for each server would be useful.'' | ||
==Curated Collections== | |||
- [http://mobidb.bio.unipd.it/about MobiDB3.0: More annotations for intrinsic disorder, conformational diversity and interactions in proteins] - MobiDB also includes manually curated disorder data along with derived and predicted data highlighted above. | |||
- [http://pedb.vib.be/ PED: Protein Ensemble Database]: " an openly accessible database for the deposition of structural ensembles of intrinsically disordered proteins (IDPs) and of denatured proteins based on nuclear magnetic resonance spectroscopy, small-angle X-ray scattering and other data measured in solution." The database of conformational ensembles describing flexible proteins. Seems stopped taking submissions in 2016. | |||
- [http://www.ideal.force.cs.is.nagoya-u.ac.jp/IDEAL/ IDEAL: Intrinsically Disordered proteins with Extensive Annotations and Literature]: "a collection of | |||
knowledge on experimentally verified intrinsically disordered" proteins. IDEAL contains manual annotations by curators on intrinsically disordered regions..."" | |||
- [http://www.disprot.org/ Disprot]: " a database of experimental evidences of disorder manually collected from literature." | |||
== Biological implications of IUPs == | == Biological implications of IUPs == | ||
