Thiolase: Difference between revisions

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<StructureSection load='4c2j' size='450' side='right' caption='Human 3-ketoacyl-CoA complex with CoA and ethylene glycol(PDB code [[4c2j]]).' scene='44/447919/Cv/7'>
<StructureSection load='4c2j' size='350' side='right' caption='Human 3-ketoacyl-CoA complex with CoA and ethylene glycol(PDB code [[4c2j]]).' scene='44/447919/Cv/7'>
== Function ==
== Function ==
Two different classes of '''thiolases''' are found.<br />
Two different classes of '''thiolases''' are found.<br />
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**[[4ubv]] – MtKCT + CoA + acetyl CoA  <br />
**[[4ubv]] – MtKCT + CoA + acetyl CoA  <br />


*Acetoacetyl-CoA thiolase
*Acetoacetyl-CoA thiolase or acetyl-CoA acetyltransferase


**[[1m4s]], [[1m4t]], [[1dlu]], [[1qfl]] - ZrACT – ''Zoogloea ramigera''<br />
**[[1m4s]], [[1m4t]], [[1dlu]], [[1qfl]] - ZrACT – ''Zoogloea ramigera''<br />
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**[[5f0v]], [[5f38]], [[4wys]] – ACT – ''Escherichia coli'' <br />
**[[5f0v]], [[5f38]], [[4wys]] – ACT – ''Escherichia coli'' <br />
**[[4o9a]], [[4o99]], [[4o9c]], [[4nzs]] – ReACT <br />
**[[4o9a]], [[4o99]], [[4o9c]], [[4nzs]] – ReACT <br />
**[[5xyj]], [[5xz5]] – yACT <br />


*Acetoacetyl-CoA thiolase complex
*Acetoacetyl-CoA thiolase complex
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**[[1wl4]] – hACT cytosolic + CoA <br />
**[[1wl4]] – hACT cytosolic + CoA <br />
**[[4xl4]] – CaACT + CoA <br />
**[[4xl4]] – CaACT + CoA <br />
 
**[[6et9]] – MtACT + PFAM DUF35 + hydroxymethylglutaryl-CoA synthase - ''Methanothermococcus thermolithotrophicus''<br />
**[[6esq]] – MtACT + CoA + PFAM DUF35 + hydroxymethylglutaryl-CoA synthase <br />
**[[6are]] – ACT + CoA + acetate - ''Aspergillus fumigatus'' <br />
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]