Transferrin: Difference between revisions
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<StructureSection load='' size=' | <StructureSection load='' size='350' side='right' caption='Glycosylated human transferrin with Fe+3 (light red), carbonate and sulfate (PDB code [[3qyt]]).' scene='48/480879/Cv/1' pspeed='8'> | ||
== Function == | == Function == | ||
'''Transferrin''' or '''serotransferrin''' (TF) is an iron-binding protein. TF delivers iron from absorption centers in the duodendum and white blood cell macrophages to all tissues<ref>PMID:2208733</ref>. '''Ovotransferrin''' (OTF) is a glycosylated TF of egg white. For details see [[Molecular Playground/Transferrin]]. | '''Transferrin''' or '''serotransferrin''' (TF) is an iron-binding protein. TF delivers iron from absorption centers in the duodendum and white blood cell macrophages to all tissues<ref>PMID:2208733</ref>. '''Ovotransferrin''' (OTF) is a glycosylated TF of egg white. For details see [[Molecular Playground/Transferrin]]. | ||
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**[[3qyt]], [[3v83]], [[4x1b]] – hTF + Fe+3 - human<br /> | **[[3qyt]], [[3v83]], [[4x1b]] – hTF + Fe+3 - human<br /> | ||
**[[4x1d]] – hTF + Yb+3 <br /> | **[[4x1d]] – hTF + Yb+3 <br /> | ||
**[[5dyh]] – hTF + Ti+4 <br /> | **[[5dyh]], [[5h52]] – hTF + Ti+4 <br /> | ||
**[[4h0w]] – hTF + Fe+3 + Bi+3<br /> | **[[4h0w]] – hTF + Fe+3 + Bi+3<br /> | ||
**[[5x5p]], [[5wtd]] – hTF + Fe+3 + Ru+3<br /> | |||
**[[5y6k]] – hTF + Fe+3 + probe<br /> | |||
**[[1suv]] – hTF + TF receptor <br /> | **[[1suv]] – hTF + TF receptor <br /> | ||
**[[3s9l]], [[3s9m]], [[3s9n]] - hTF (mutant) + TF receptor<br /> | **[[3s9l]], [[3s9m]], [[3s9n]] - hTF (mutant) + TF receptor<br /> | ||
**[[6d03]], [[6d04]], [[6d05]] – TF + TF receptor - ''Pasmodium vivax'' - Cryo EM<br /> | |||
*Transferrin N lobe | *Transferrin N lobe | ||