6b66: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6b66 is ~~ON HOLD until Paper Publication~~

==IMPase (AF2372) R92Q/K164E with 400 mM Glutamate==

~~Authors~~: ~~Goldstein~~, R.I., ~~Roberts~~, M.

== Structural highlights ==

<table><tr><td colspan='2'>[[6b66]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B66 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B66 FirstGlance]. <br>

~~Description: IMPase (AF2372) R29Q/K164E with 400 mM Glutamate~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b66 OCA], [http://pdbe.org/6b66 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b66 RCSB], [http://www.ebi.ac.uk/pdbsum/6b66 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b66 ProSAT]</span></td></tr>

[[Category: Goldstein, R.I]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/BSUHB_ARCFU BSUHB_ARCFU]] Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, both D and L isomers of inositol-1-phosphate (I-1-P), 2'-AMP, pNPP, inositol-2-phosphate, beta-glycerol phosphate, and alpha-D-glucose-1-phosphate. Cannot hydrolyze glucose-6-phosphate and fructose-6-phosphate. May be involved in the biosynthesis of a unique osmolyte, di-myo-inositol 1,1-phosphate.<ref>PMID:10747806</ref> <ref>PMID:11062561</ref> <ref>PMID:11940584</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Goldstein, R I]]

[[Category: Roberts, M]]

[[Category: Hydrolase]]

[[Category: Inositol monophosphatase]]

[[Category: Osmolyte binding protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6b66 is ON HOLD  until Paper Publication
+==IMPase (AF2372) R92Q/K164E with 400 mM Glutamate==
+<StructureSection load='6b66' size='340' side='right' caption='[[6b66]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-Authors: Goldstein, R.I., Roberts, M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6b66]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B66 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B66 FirstGlance]. <br>
-Description: IMPase (AF2372) R29Q/K164E with 400 mM Glutamate
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b66 OCA], [http://pdbe.org/6b66 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b66 RCSB], [http://www.ebi.ac.uk/pdbsum/6b66 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b66 ProSAT]</span></td></tr>
-[[Category: Goldstein, R.I]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/BSUHB_ARCFU BSUHB_ARCFU]] Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, both D and L isomers of inositol-1-phosphate (I-1-P), 2'-AMP, pNPP, inositol-2-phosphate, beta-glycerol phosphate, and alpha-D-glucose-1-phosphate. Cannot hydrolyze glucose-6-phosphate and fructose-6-phosphate. May be involved in the biosynthesis of a unique osmolyte, di-myo-inositol 1,1-phosphate.<ref>PMID:10747806</ref> <ref>PMID:11062561</ref> <ref>PMID:11940584</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Goldstein, R I]]
 [[Category: Roberts, M]]
+[[Category: Hydrolase]]
+[[Category: Inositol monophosphatase]]
+[[Category: Osmolyte binding protein]]